Alzheimer's is a devastating neurodegenerative disease that robs individuals of their memories and cognitive abilities. However, amidst the challenges, a glimmer of hope emerges in the form of Dihexa.
In this blog, we will delve into the fascinating connection between Alzheimer's and Dihexa, exploring the possibilities it holds in offering new avenues of support and treatment. Read on to learn more!
What is Dihexa?
Dihexa is an oligopeptide drug derived from angiotensin IV that has shown potential in improving cognitive function, particularly in animal models of Alzheimer's disease-like mental impairment.[1][2]
It binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met
Here are some key points about Dihexa:
It has been found to be seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF) in an assay of neurotrophic activity.
Dihexa has been developed to explore its potential in improving cognitive functions in brain disorders, including Alzheimer's disease, through increased synaptogenesis.[1]
It has the ability to repair damages found in the synapse between neurons, which is beneficial for cognitive function.[1][3]
Dihexa is orally active, penetrates the blood-brain barrier, and facilitates memory consolidation and retrieval.
It has shown promise in overcoming memory and motor dysfunctions by augmenting synaptic connectivity and forming new functional synapses.
Dihexa has been studied for its potential applications in other neurodegenerative diseases or brain traumas where neuronal connections are lost.[4]
While Dihexa has shown benefits, it is important to note that it may have side effects and should be used under medical supervision.[4]
It is worth mentioning that Dihexa is still in the developmental stage and further research is needed to fully understand its potential benefits and risks.
Clinical Research on Dihexa
Clinical research on Dihexa, an oligopeptide drug derived from angiotensin IV, has shown promising results in improving cognitive function, particularly in animal models of Alzheimer's disease-like mental impairment.[2][5][6]
Here are some key findings from some research about it:
Cognitive Function Improvement
Dihexa has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment.[2][6] It has shown the ability to enhance memory consolidation and retrieval.[4]
Neurotrophic Activity
In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF).[2]
This suggests that Dihexa has a strong potential for promoting the growth and survival of neurons.
Synaptic Connectivity
Dihexa has shown promise in overcoming memory and motor dysfunctions by augmenting synaptic connectivity and forming new functional synapses.[4][6]
It has the ability to repair damages found in the synapse between neurons, which is beneficial for cognitive function.[5][6]
Safety Profile
Short-duration safety studies with Dihexa have uncovered no apparent toxicity, including neoplastic induction. However, it is important to note that further research is needed to fully understand the long-term safety and potential side effects of Dihexa.[4]
It is worth mentioning that while the results of animal studies are promising, clinical trials in humans are still needed to determine the efficacy and safety of Dihexa for cognitive improvement in humans.
Additionally, Dihexa is a developmental drug and is not currently approved for clinical use. Therefore, it should only be used under medical supervision and guidance.[4]
Benefits of Dihexa
Here are some of the benefits of Dihexa:
Enhanced Creative Thinking: Dihexa has been found to enhance creative thinking.[7][8]
Improved Social Intuition and Interpersonal Skills: Dihexa has been shown to improve social intuition and interpersonal skills.[7][8]
Ability to Better Manage or Eliminate Depression: Dihexa has been found to help better manage or eliminate depression.[7]
Reduced Neurological Damage: Dihexa has been found to reduce the neurological damage induced by Alzheimer's disease.[9]
Enhanced Cognition in Seniors with Cognitive Difficulties: Dihexa has been found to enhance cognition in seniors with cognitive difficulties.[9]
Benefit in Treating Parkinson's Disease: Dihexa has shown benefit in treating Parkinson's disease.[9]
Improved Problem-Solving Skills: Dihexa has been found to improve problem-solving skills.[9]
Enhanced Creativity: Dihexa has been found to enhance creativity.[8][9]
Potent Neurotrophic Activity: Dihexa has been found to be seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF) in an assay of neurotrophic activity.[7][10] This suggests that Dihexa has a strong potential for promoting the growth and survival of neurons.
It is important to note that while Dihexa has shown benefits, it is still in the developmental stage and further research is needed to fully understand its potential benefits and risks.
Additionally, Dihexa is not currently approved for clinical use and should only be used under medical supervision and guidance.[2]
How does Dihexa work?
Dihexa is a nootropic drug that is designed to enhance certain cognitive functions, improve mental stamina, and boost both short- and long-term memory capacity.[7]
It is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met.[4]
Dihexa works by penetrating the blood-brain barrier and facilitating memory consolidation and retrieval.[1][4]
It is also believed to create new synapses, which can repair damages found in the synapse that is just between the neurons.[1][9]
Dihexa shows promise in overcoming memory and motor dysfunctions by augmenting synaptic connectivity via the formation of new functional synapses.[4]
It has been shown to enhance the acquisition, consolidation, and recall of learning and memory in animal models when administered centrally or peripherally.[7]
Although Dihexa seems to have a wealth of benefits, it isn’t without its side effects.[4]
Potential Side Effects
Some of the potential side effects of Dihexa include:
- Reduced attention span
- Irritability
- Mood swings
- Changes in taste
- Increased anxiety
- Nausea
- Insomnia
It is also worth noting that one Reddit user reported experiencing attention deficit issues while using Dihexa, which they compared to the complications exhibited by extended NSI-189 supplementation.[4]
It is important to consult with a healthcare professional before using Dihexa, especially if you have any pre-existing medical conditions or are taking other medications.
Dosage and Administration
Dosage and administration of Dihexa may vary depending on the person and use. Dihexa is supplied in capsules and a topical gel.[9]
The average ranges of Dihexa dosage are between 8 and 45 milligrams taken orally.[1][3][4][12]
Supplement companies selling Dihexa as a research chemical often suggest taking 10 to 20 mg a day, while the drug manufacturers recommend 10 mg to 20 mg once a week.[12]
The recommended dosage of DIHEXA can range from 5 mg to 20 mg.
Exact dosing may vary based on individual needs and use.[9]
- For capsules, the strengths are 2 mg, 10 mg, 20 mg, and 25 mg.[9]
- For the cream, apply 0.5-1mL (or 2-4 clicks) to your inner forearm daily and rub it in until it is absorbed.[1]
It is important to consult with a healthcare professional before using Dihexa, especially if you have any pre-existing medical conditions or are taking other medications.[9]
Frequently Asked Questions
What are peptides for Alzheimer's disease?
One of the specific peptides for Alzheimer's disease is Beta-amyloid peptide (Aβ). This peptide is closely associated with the formation of plaques in the brain, which are characteristic features of Alzheimer's.
Another noteworthy peptide is Dihexa, which has garnered attention for its potential in supporting brain health and memory retention. While these peptides are still being studied, their targeted actions against Alzheimer's-related processes offer hope for future therapeutic interventions.
What is the chemical name for Dihexa?
The chemical name for Dihexa is N-hexanoic-Tyr-Ile-(6) aminohexanoic amide.
This compound has been studied for its potential in promoting brain health and memory retention, making it a subject of interest in Alzheimer's and cognitive research.
Conclusion
In conclusion, Dihexa emerges as a promising compound with significant implications for brain health and memory retention.
Its potential to combat Alzheimer's and support cognitive function has sparked intrigue in the scientific community.
While still in the research phase, Dihexa's targeted actions against Alzheimer's-related processes offer hope for the development of future therapeutic interventions.
As we continue to unravel the mysteries of this remarkable peptide, staying informed about the latest advancements in Alzheimer's research and potential treatments will be crucial.
By keeping a watchful eye on developments in Dihexa's journey, we can remain hopeful for breakthroughs that may positively impact countless lives affected by cognitive decline.
References
- Dihexa: The Alzheimer’s Disease Helping Peptide. Retrieved from https://vitality-sciences.com/peptides/what-is-dihexa-alzheimers-disease-helping-peptide/
- Dihexa. Retrieved from https://hormonetherapyntx.com/product/dihexa/
- Dihexa. Retrieved from https://www.genemedics.com/dihexa
- Peptide Therapy. Retrieved from https://neuronmedical.com/peptide-therapy-dihexa-selank-semax-thousand-oaks/
- Development of Small Molecule Hepatocyte Growth Factor Mimetics f… Retrieved from https://www.michaeljfox.org/grant/development-small-molecule-hepatocyte-growth-factor-mimetics-treatment-parkinsons-disease
- Dihexa. Retrieved from https://smithcw.com/scw-medical/brain-recovery-support/dihexa/
- Enhance Your Brain Function With Dihexa. Retrieved from https://www.amisantabarbara.com/dihexa
- Dihexa Peptide Therapy. Retrieved from https://aspirerejuvenation.com/services/dihexa-peptide-therapy/
- Dihexa Cognitive Repair Peptide. Retrieved from https://pramahtampa.com/services/metabolic/peptide-therapy/dihexa-2/
- Peptide of the Week: Unveiling the Remarkable Benefits of Dihexa. Retrieved from https://burickcenter.com/peptide-of-the-week-unveiling-the-remarkable-benefits-of-dihexa/
- Dihexa: Usage, Side Effects and Dosage. Retrieved from https://rhtp.org/dihexa/
- Dihexa: Review of Benefits, Uses, Dosage, & Side Effects. Retrieved from https://wholisticresearch.com/dihexa/
